Ultrasound-guided fine needle aspiration versus non-aspiration techniques in the evaluation of solid thyroid nodules

Abstract Background Comparison between the Fine Needle Non-Aspiration Cytology (FNNAC) and Aspiration (FNAC) in acquiring ultrasound-guided fine needle cytology (FNC) samples from solid thyroid nodules to determine better technique, hence improving sample quality aiming decrease number of unnecessary thyroidectomy operations. Results Prospective study showed statistically significant increase cellular yield, preservation architecture trauma along with total FNNAC ( P value = 0.32, 0.004, 0.011, 0.21 respectively), insignificant difference background blood 0.8). Regarding convenience, was found be more convenient for both patient (syringe is not seen by reducing discomfort) operator (better handling fewer maneuvres). Conclusions FNC an approved sensitive cost-effective method evaluate nodules, technique improvement compared FNAC.